This article lists fourteen open problems in artificial life, each of which is a grand challenge requiring a major advance on a fundamental issue for its solution. Each problem is briefly explained, and, where deemed helpful, some promising paths to its solution are indicated.

artificial life, evolution, self-organization, emergence, self-replication, autopoeisis, digital life, artificial chemistry, selection, evolutionary learning, ecosystems, biosystems, astrobiology, evolvable hardware, dynamical hierarchies, origin of life, simulation, cultural evolution, information theory
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© 2001 Massachusetts Institute of Technology
2000
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