Yale University and the National University of Singapore (NUS) agreed in 2011 to open Yale-NUS College, an autonomous liberal arts college within NUS. As the College's first president, I recount in this essay some of the successes and challenges of creating the College, which opened in 2013, and the decision of NUS in 2021 to end the partnership as of 2025. I analyze the College's educational offerings, the political controversies surrounding its establishment and eventual closure, the finances of a small-scale, elite college within a large public university, and the broad social changes that contributed to the College's fate.