The article examines curatorial practices in regard to graphic design and posters—a subject only sparsely covered by poster research. It investigates how urban, environmental structures can work as guidelines for curating posters and ephemerals in museums. By applying an ecological view to design, it stresses the reciprocal relationship of humans with their built and product-designed environments and suggests this approach to be viable for curatorial work. It further demonstrates the point in regard to a recent event, the exhibition Spot on! British Posters from the Interwar Years, which was exhibited at the Danish Poster Museum in 2015–2016 and initiated by author and graphic designer Michael Jensen.