In his 2015 Research Through Design provocation, Tim Ingold invites his audience to think with string, lines, and meshworks. In this article I use Ingold's concepts to explore an orientation to design—one that threads through both Ingold's ideas and Vinciane Despret's vivid and moving accounts of human-animal relations. This is a “thinking and doing” through design that seeks to be expansive to the capacities of humans and non-humans in relation to one another.