This article critically reviews how we think about design in technology and service innovation. Human-centered design has emerged in this science-driven field as a way to include the interests of humans and their needs in production processes. As such, design has a considerable effect on the development of new technologies and services. Making visible the agency of design in these practices thus is of immense importance. A gap remains in the ability of current concepts of design to visualize and conceptualize design agency. Therefore, drawing on concepts of materiality in design and practice, this article proposes a framework that makes design agency visible.