Special Issue on Imaging Genetics
Imaging Neuroscience Special Issue on Imaging Genetics
Editors:
- Mbemba Jabbi (Managing Guest Editor; University of Texas at Austin Dell Medical School)
- Neda Jahanshad (University of Southern California)
- Tian Ge (Massachusetts General Hospital and Harvard Medical School)
- Qiang Luo (Fudan University)
- Monica Rosenberg (Executive SI Editor; The University of Chicago)
Human genetic studies have made significant progress in shedding light on how genes influence bodily systems in health and disease. Yet, the role genes play in shaping the human brain’s ability in complex behavioral functions and risk for dysfunctions across the lifespan remain poorly understood. Given the limitations of genetic studies in the living human brain, non-invasive neuroimaging studies that integrate genetics with brain anatomical, physiological, molecular, and behavioral measures offer a uniquely promising avenue for elucidating the ways in which genes contribute to the brain’s regulation of behavior in health and disease. The scope of this Special Issue on Imaging Genetics includes basic, translational, clinical, and integrative systems neuroscience research that explores the relationships between human genetic variants (e.g., single nucleotide polymorphisms (SNPs), copy number variations (CNVs), methylation patterns, and other relevant factors), brain imaging features, and behavioral phenotypes in both health and disease. The issue aims to bridge the knowledge gap between genetic variation and the brain’s anatomical, physiological, or molecular underpinnings of complex behaviors. The contributions from this special issue will inform future neurobiological and clinical neuroscience studies, facilitate mechanistic understanding, and inspire novel therapeutic approaches.
