There is great interest in oil-in-water droplets as simple systems that display astonishingly complex behaviours. Recently, we reported a chemorobotic platform capable of autonomously exploring and evolving the behaviours these droplets can exhibit. The platform enabled us to undertake a large number of reproducible experiments, allowing us to probe the non-linear relationship between droplet composition and behaviour. Herein we introduce this work, and also report on the recent developments we have made to this system. These include new platforms to simultaneously evolve the droplets’ physical and chemical environments and the inclusion of selfreplicating molecules in the droplets.