In this work, we propose a framework that derives the configuration of an artificial, compartmentalized, cell-like structure in order to maximize the yield of a desired output reactant given a formal description of the chemistry. The configuration of the structure is then used to compile G-code for 3D printing of a microfluidic platform able to manufacture the aforementioned structure. Furthermore, the compiler output includes a set of pressure profiles to actuate the valves at the input of the microfluidic platform. The work includes an outline of the steps involved in the compilation process and a discussion of the algorithms needed for each step. Finally, we provide formal, declarative languages for the input and output interfaces of each of these steps.

We present a model for the spread, transmission and competition of skills with an emphasis on the role of spatial mobility of individuals. From a methodological point of view, we seek mathematical and computational simplicity in the sense of a minimal model. This minimalism lets us use a infinite dimensional simplex space and not a Euclidean space as underlying structure. Such a simplex captures the essentials of spatial heterogeneity without the mathematical difficulties of neighborhood structures. In the presented model, individuals may have no skill or either skill A or B. Individuals are born unskilled and may acquire skills by learning from a skilled individual. Skill A results in a small reproductive advantage and is easy to transmit (teaching happens at high rate), whereas skill B is harder to teach but results in a high benefit. The model exhibits a rich behavior; after an initial transient, the system settles to a fix point (constant distribution of skills), whereby the distribution of skills depends on a mobility parameter m. We observe different regimes, and as the main result, we conclude that for some settings of the system parameters, the spread of the (harder to learn but more beneficial) skill B is only possible within a specific range of the mobility parameter. From a technical point of view, this paper presents the application of the PRESS–method (probability reduced evolution of spatially resolved species) that enables the study of spatial effects in a very efficient manner. We analyze the consequences of spatial organization and argue that we can study aspects of social dynamics in an infinite dimensional simplex space. In spite of this maybe daunting name, the dynamics on such a structure is comparably easy to implement. The model we present is far from reflecting all the details of human interaction. On the contrary, we deliberately tailored the model to be as simple as possible from a mathematical point of view (but still reflecting central properties of spatial organization). This approach is guided by physics, where seemingly simple models which obviously don’t reflect the true physical behavior of a system (such as the Ising model) are nevertheless suited to reveal fundamental aspects and limiting cases of the real world.

The latest report from the Intergovernmental Panel on Climate Change (IPCC) estimated that humanity has a time window of about 12 years in order to prevent anthropogenic climate change of catastrophic magnitude. Green house gas emission from air travel, which is currently rising, is possibly one of the factors that can be most readily reduced. Within this context, we advocate for the re-design of academic conferences in order to decrease their environmental footprint. Today, virtual technologies hold the promise to substitute many forms of physical interactions and increasingly make their way into conferences to reduce the number of travelling delegates. Here, we present the results of a survey in which we gathered the opinion on this topic of academics worldwide. Results suggest there is ample room for challenging the (dangerous) business-as-usual inertia of scientific lifestyle.