Though virtually ignored in the historiography, Brazil played an intriguing role in the politics and diplomacy of the Cuban missile crisis and in U.S. Cuban relations during the Kennedy administration. In the years after Fidel Castro took power, successive Brazilian governments tried secretly to mediate between Washington and Havana as their mutual confrontation intensified. Newly available U.S., Brazilian, Cuban, and other sources reveal that this role climaxed during the missile crisis, as John F. Kennedy clandestinely sought to employ Brazil to transmit a message to Castro. In turn, Brazil, which was also promoting a Latin American denuclearization scheme at the United Nations as a possible means of resolving the crisis, sought to broker a formula for U.S. Cuban reconciliation that would heighten the prestige of its own “independent”policy in the Cold War. Ultimately, these efforts failed, but they shed light on previously hidden aspects of both the missile crisis and the triangular U.S. Cuban-Brazilian relationship. This is the concluding part of a two-part article.