The aim of this study was to examine whether oscillatory activity in the theta-band is relevant for selective visuospatial attention when there is a need for the suppression of interfering and distracting information. A variant of the Eriksen flanker task was employed with bilateral arrays: one array consisting of a target and congruent or incongruent flankers and the second array consisting of neutral distractors. The bilateral arrays were preceded either by a 100% valid spatial cue or by a neutral cue. In the cue–target interval, a major burst in medial frontal theta power was observed, which was largest in the spatial cue condition. In the latter condition, additionally a posterior theta increase was observed that was larger over sites ipsilateral to the forthcoming target array. Functional connectivity analyses revealed that this pretarget posterior theta was related to the midfrontal theta. No such effects were observed in the neutral cue condition. After onset of the bilateral arrays, a major burst in posterior theta activity was observed in both cue conditions, which again was larger above sites ipsilateral to the target array. Furthermore, this posterior theta was in all cases related to the midfrontal theta. Taken together, the findings suggest that a fronto-posterior theta network plays an important role in the suppression of irrelevant and conflicting visual information. The results also suggest that the reciprocal relation between visuospatial attention and executive response control may be closer than commonly thought.

This study aimed to trace the neural basis of proactive and preemptive adjustments of executive control and their effects on online processing of response conflict. In two EEG experiments, participants performed the flanker task with predictive cueing of conflict. The following questions were addressed: “Does conflict cueing improve performance?” We observed improved behavioral performance in the predictive condition, suggesting that participants proactively utilized the cues to prepare for the upcoming demands. “How is conflict processing affected by predictive cueing?” Conflict-related modulations of midfrontal N2 and theta power were smaller in the predictive than in the neutral condition. This suggests that proactive control suppressed the impact of incongruent flankers so that the conflict was reduced, and so was the involvement of online control. “Is proactive control implemented through preactivation of online control?” Conflict cueing increased midfrontal theta power also before target onset, suggesting preactivation of the control processes beforehand. “Do proactive and reactive control depend on common or unique processes?” Unlike the online control, the proactive control triggered a burst of theta power in the right hemisphere's dorsal and ventral lateral prefrontal cortices, connected with the midfrontal area via theta phase coherence. This indicates that the two control modes involve partially unique but coordinated neural processes. “Is preemptive control implemented through modulations of visual processing?” Predictive cueing modulated both the pretarget preparatory alpha desynchronization and the target selection-related posterior contralateral negativity (N2pc and sustained posterior contralateral negativity), in line with the hypothesis of preemptive tuning of sensory selection aimed at reducing the impact of conflicting stimuli.

This EEG study investigates the electrophysiological activity underlying processes of stimulus and response selection, and their executive orchestration via long-range functional connectivity under conflict condition, in order to shed more light on how these brain dynamics shape individual behavioral performance. Participants ( n = 91) performed a modified flanker task, in which bilateral visual stimulation and a bimanual response pattern were employed to isolate the stimulus and response selection-related lateralized activity. First, we identified conflict-related markers of task-relevant processes; most importantly, the stimulus and response selection were evidenced by contra–ipsilateral differences in visual and motor activity, respectively, and executive control was evidenced by modulations of midfrontal activity. Second, we identified conflict-related functional connectivity between midfrontal and other task-relevant areas. The results showed that interregional phase synchronization in theta band was centered at the midfrontal site, interpreted here as a “hub” of executive communication. Importantly, the theta functional connectivity was more robust under the condition of increased demands for stimulus and response selection, including connectivity between the medial frontal cortex and the lateral frontal and motor areas, as well as cross-frequency theta–alpha coupling between the medial frontal cortex and contralateral visual areas. Third, we showed that individual differences in the measured conflict-related EEG activity, particularly the midfrontal N2, theta power, and global theta connectivity, predict the behavioral efficiency in conflict resolution.