Skip Nav Destination
Close Modal
Update search
NARROW
Format
Journal
TocHeadingTitle
Date
Availability
1-2 of 2
Brigitte Landeau
Close
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Sort by
Journal Articles
Structural and Metabolic Correlates of Episodic Memory in Relation to the Depth of Encoding in Normal Aging
UnavailablePublisher: Journals Gateway
Journal of Cognitive Neuroscience (2009) 21 (2): 372–389.
Published: 01 February 2009
Abstract
View articletitled, Structural and Metabolic Correlates of Episodic Memory in Relation to the Depth of Encoding in Normal Aging
View
PDF
for article titled, Structural and Metabolic Correlates of Episodic Memory in Relation to the Depth of Encoding in Normal Aging
This study set out to establish the relationship between changes in episodic memory retrieval in normal aging on the one hand and gray matter volume and 18 FDG uptake on the other. Structural MRI, resting-state 18 FDG-PET, and an episodic memory task manipulating the depth of encoding and the retention interval were administered to 46 healthy subjects divided into three groups according to their age (young, middle-aged, and elderly adults). Memory decline was found not to be linear in the course of normal aging: Whatever the retention interval, the retrieval of shallowly encoded words was impaired in both the middle-aged and the elderly, whereas the retrieval of deeply encoded words only declined in the elderly. In middle-aged and elderly subjects, the reduced performance in the shallow encoding condition was mainly related to posterior mediotemporal volume and metabolism. By contrast, the impaired retrieval of deeply encoded words in the elderly group was mainly related to frontal and parietal regions, suggesting the adoption of inefficient strategic processes.
Journal Articles
Publisher: Journals Gateway
Journal of Cognitive Neuroscience (2001) 13 (5): 670–686.
Published: 01 July 2001
Abstract
View articletitled, Visual Priming Within and Across Symbolic Format Using a Tachistoscopic Picture Identification Task: A PET Study
View
PDF
for article titled, Visual Priming Within and Across Symbolic Format Using a Tachistoscopic Picture Identification Task: A PET Study
The present work was aimed at characterizing picture priming effects from two complementary behavioral and functional neuroimaging (positron emission tomography, PET) studies. In two experiments, we used the same line drawings of common living/nonliving objects in a tachistoscopic identification task to contrast two forms of priming. In the within-format priming condition (picture-picture), subjects were instructed to perform a perceptual encoding task in the study phase, whereas in the cross-format priming condition (word-picture), they were instructed to perform a semantic encoding task. In Experiment 1, we showed significant priming effects in both priming conditions. However, the magnitude of priming effects in the same-format/perceptual encoding condition was higher than that in the different-format/semantic encoding condition, while the recognition performance did not differ between the two conditions. This finding supports the existence of two forms of priming that may be subserved by different systems. Consistent with these behavioral findings, the PET data for Experiment 2 revealed distinct priming-related patterns of regional cerebral blood flow (rCBF) decreases for the two priming conditions when primed items were compared to unprimed items. The same-format priming condition involved reductions in cerebral activity particularly in the right extrastriate cortex and left cerebellum, while the different-format priming condition was associated with rCBF decreases in the left inferior temporo-occipital cortex, left frontal regions, and the right cerebellum. These results suggest that the extrastriate cortex may subserve general aspects of perceptual priming, independent of the kind of stimuli, and that the right part of this cortex could underlie the same-format-specific system for pictures. These data also support the idea that the cross-format/semantic encoding priming for pictures represents a form of lexico-semantic priming subserved by a semantic neural network extending from left temporo-occipital cortex to left frontal regions. These results reinforce the distinction between perceptual and conceptual priming for pictures, indicating that different cerebral processes and systems are implicated in these two forms of picture priming.