The investigation of the role of Art as a Catalyst at the intersection of science and technology has become a global focal point over the last decade. The Balance-Unbalance 2013 international conference explored this issue in depth. “Artists as Catalysts” was the main topic of the 2013 Ars Electronica Festival - strong evidence of significant interdisciplinary progress. Nevertheless the question remains: How is art, science and technology changing in the process? Does cross-disciplinary artist-initiated collaboration function as a catalyst in this setting? This paper briefly examines these issues based on personal participatory experience.