Trust Me, I’m an Artist (TMIAA) is a European-based project devoted to developing “Ethical Frameworks for Artists, Cultural Institutions and Audiences Engaged in the Challenges of Creating and Experiencing New Art Forms in Biotechnology and Biomedicine.” As such it brings together a wide variety of interested parties to debate and, hopefully to some extent, resolve ethical issues arising at the intersection of art, science and biomedicine. Leonardo hosts a selection of articles by the artists and curators reporting about the project and the experience.