The author discusses Biopoiesis , a cybernetic art project that explores the relationships between structure, matter and self-organization. Based on the work of cyberneticist Gordon Pask, the project features the construction of simple computational devices that harness an electrochemical reaction. The design and construction of the system is discussed, as well as its conceptual underpinnings and historical context. The relevance of Pask’s electrochemical works to artmaking is also explored.