As our civilization continues to dive deeper into the information age, making sense of complex data becomes critical. This work takes on this challenge by means of a novel method based on complete inter disciplinarity, design process and built-in evaluations. The result is the design, construction, testing and deployment of data environments supporting real-time decision-making in such diverse domains as anesthesiology and live art performance. Fundraising success, technology licensing, market implementation and many live art performances provide evidence of the great potential of committed interdisciplinary work for advancing science, art and technology while benefiting society at large.