Forming part of the University of Colorado Boulder’s Grand Challenge initiative, the Nature, Environment, Science & Technology (NEST) Studio for the Arts is a new endeavor that explores the interrelation, generative overlaps and productive differences between the sciences and the arts by means of exhibitions, student work, lectures, panels, courses and events. Operationally launched in the summer of 2018, NEST seeks efforts that engage with central questions regarding alternative and constructive ways of passing information and methodologies back and forth between the two worlds. Efforts such as these are key to advancing cross-disciplinary efforts in siloed campuses across the nation.