This paper introduces critical elements in the substantial, albeit mostly unpublished, correspondence between cultural anthropologist Edward T. Hall and media theorist Marshall McLuhan related to artistic practice with emerging media technologies in the 1960s. It contextualizes their exchange within the broader theoretical discourses and artistic practices surrounding systems theory and media technology and highlights intersections between Hall and McLuhan’s theoretical frameworks related to concepts of indeterminism, systems theory, and cybernetics in technology-based, kinesthetic, multisensory mediated environments in the 1960s. It particularly focuses on overlapping conceptual approaches toward the interrelation between the individual, the socio-cultural environment, and the emerging media-technological ecosystem.