In this letter, we provide a study of learning in a Hilbert space of vector-valued functions. We motivate the need for extending learning theory of scalar-valued functions by practical considerations and establish some basic results for learning vector-valued functions that should prove useful in applications. Specifically, we allow an output space Y to be a Hilbert space, and we consider a reproducing kernel Hilbert space of functions whose values lie in Y . In this setting, we derive the form of the minimal norm interpolant to a finite set of data and apply it to study some regularization functionals that are important in learning theory. We consider specific examples of such functionals corresponding to multiple-output regularization networks and support vector machines, for both regression and classification. Finally, we provide classes of operator-valued kernels of the dot product and translation-invariant type.