The sensory rearrangement theory announced that a mismatch between the current visual inputs and the visual exposure history might trigger or aggravate the visually induced motion sickness (VIMS). However, this has not been explicitly investigated through perception experiments. This study investigates the effect of mismatches between 3D content acquisition and perception on VIMS. Two types of mismatches between the camera field of view and the eye field of view were compared with the match type, and the mismatch types are the conditions that configured the camera field of view to be larger or smaller than the eye field of view. A perception experiment was executed with 21 participants, and the subjective SSQ, five-scale VIMS level rating, and objective postural instability were adopted as the evaluation metrics. The mismatches were found to have a significant effect ( p < 0.05) on the VIMS symptom based on the results of subjective VIMS level rating and objective postural instability evaluations. Mismatches between 3D content acquisition and perception cause more VIMS. This knowledge highlights the importance of perfect configuration matches in 3D content acquisition, display, and perception for eliminating the potential VIMS aggravation effect.