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Table 1. 
Participant characteristics.
VariableASD Mean ± SD [range]TD Mean ± SD [range]Significance
N 145 121   
Age 16.47 ± 6.46 [7.13–39.10] 16.03 ± 5.70 [6.47–31.78] t(264) = 0.58, p = 0.56 
IQ 107.57 ± 16.32 [76–148] 110.08 ± 11.61 [80–133] t(264) = −1.43, p = 0.15 
Mean FD 0.07 ± 0.04 [0.02–0.19] 0.07 ± 0.03 [0.03–0.19] t(264) = 1.32, p = 0.19 
Percent FD > 0.2 mm 4.69 ± 5.27 [0–19.33] 3.92 ± 1.29 [0–19.33] t(264) = 1.29, p = 0.20 
Handedness 120 RH 21 LH 109 RH 10 LH X2(1, N = 266) = 0.52, p = 0.13 
Eye status 121 open 24 closed 95 open 26 closed X2(1, N = 266) = 1.38, p = 0.35 
Scan site NYU: 59 SDSU: 11 TRINITY: 18 UM: 26 USM: 31 NYU: 52 SDSU: 10 TRINITY: 16 UM: 29 USM: 14 X2(4, N = 266) = 5.07, p = 0.28 
Medication use 27 yes 86 no 32 unknown 0 yes 106 no 15 unknown N/A 
Comorbidities 28 yes 117 no/unknown 0 yes 121 no/unknown N/A 
ADOS Total 11.69 ± 3.68 [5–22] (N = 118) 1.14 ± 1.17 [0–4] (N = 14) t(130) = 10.64, p < 0.001 
ADOS Communication 3.89 ± 1.55 [0–8] (N = 100) 0.50 ± 0.65 [0–2] (N = 14) t(112) = 8.06, p < 0.001 
ADOS Social 7.89 ± 2.81 [2–14] (N = 100) 0.64 ± 0.84 [0–3] (N = 14) t(112) = 9.56, p < 0.001 
ADOS RRB 2.04 ± 1.46 [0–7] (N = 98) 0.07 ± 0.27 [0–1] (N = 14) t(110) = 5.00, p < 0.001 
ADI-R Social 19.07 ± 5.44 [7–30] (N = 108) N/A N/A 
ADI-R Verbal 15.38 ± 4.36 [2–25] (N = 109) N/A N/A 
ADI-R RRB 5.66 ± 2.60 [0–12] (N = 109) N/A N/A 
SRS 92.56 ± 31.00 [26–164] (N = 89) 20.59 ± 12.43 [1–56] (N = 49) t(136) = 15.56, p < 0.001 
VariableASD Mean ± SD [range]TD Mean ± SD [range]Significance
N 145 121   
Age 16.47 ± 6.46 [7.13–39.10] 16.03 ± 5.70 [6.47–31.78] t(264) = 0.58, p = 0.56 
IQ 107.57 ± 16.32 [76–148] 110.08 ± 11.61 [80–133] t(264) = −1.43, p = 0.15 
Mean FD 0.07 ± 0.04 [0.02–0.19] 0.07 ± 0.03 [0.03–0.19] t(264) = 1.32, p = 0.19 
Percent FD > 0.2 mm 4.69 ± 5.27 [0–19.33] 3.92 ± 1.29 [0–19.33] t(264) = 1.29, p = 0.20 
Handedness 120 RH 21 LH 109 RH 10 LH X2(1, N = 266) = 0.52, p = 0.13 
Eye status 121 open 24 closed 95 open 26 closed X2(1, N = 266) = 1.38, p = 0.35 
Scan site NYU: 59 SDSU: 11 TRINITY: 18 UM: 26 USM: 31 NYU: 52 SDSU: 10 TRINITY: 16 UM: 29 USM: 14 X2(4, N = 266) = 5.07, p = 0.28 
Medication use 27 yes 86 no 32 unknown 0 yes 106 no 15 unknown N/A 
Comorbidities 28 yes 117 no/unknown 0 yes 121 no/unknown N/A 
ADOS Total 11.69 ± 3.68 [5–22] (N = 118) 1.14 ± 1.17 [0–4] (N = 14) t(130) = 10.64, p < 0.001 
ADOS Communication 3.89 ± 1.55 [0–8] (N = 100) 0.50 ± 0.65 [0–2] (N = 14) t(112) = 8.06, p < 0.001 
ADOS Social 7.89 ± 2.81 [2–14] (N = 100) 0.64 ± 0.84 [0–3] (N = 14) t(112) = 9.56, p < 0.001 
ADOS RRB 2.04 ± 1.46 [0–7] (N = 98) 0.07 ± 0.27 [0–1] (N = 14) t(110) = 5.00, p < 0.001 
ADI-R Social 19.07 ± 5.44 [7–30] (N = 108) N/A N/A 
ADI-R Verbal 15.38 ± 4.36 [2–25] (N = 109) N/A N/A 
ADI-R RRB 5.66 ± 2.60 [0–12] (N = 109) N/A N/A 
SRS 92.56 ± 31.00 [26–164] (N = 89) 20.59 ± 12.43 [1–56] (N = 49) t(136) = 15.56, p < 0.001 
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