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Table 3.

Aging data: Estimates, standard errors (SE), and p values for the original univariate mixed-model fit to rest data and new multivariate fit to rest (and visual) data

Parameter l₁ = rest	Rest (univariate)			Rest (with visual)^a
Parameter l₁ = rest	Estimate	SE	p value*	Estimate	SE	p value*
β_rl₁,0	−0.3141	0.0569	<0.0001	−0.2488	0.0448	<0.0001
β_rl₁,C	0.7807	0.3424	0.0355	*7.1274*	1.8466	*0.0004*
β_rl₁,EGlob	32.6231	2.3322	<0.0001	30.6695	1.3489	<0.0001
β_rl₁,k	−1.4442	0.1522	<0.0001	−1.5229	0.1782	<0.0001
β_rl₁,Q	−0.7345	1.1361	0.5179	−0.6460	0.9376	*0.4923*
β_rl₁,l	1.1598	0.0785	<0.0001	1.3824	0.0907	<0.0001
β_rl₁,age	−0.0438	0.0773	0.5709	−0.0806	0.0792	0.4229
β_rl₁,sex	−0.0085	0.0825	0.9178	−0.0452	0.0658	*0.4923*
β_rl₁,educ	0.0027	0.0103	0.7954	0.0071	0.0097	0.4923
β_rl₁,dist	−1.4266	0.0572	<0.0001	−1.4648	0.0530	<0.0001
β_rl₁,dist²	2.6558	0.1417	<0.0001	2.6309	0.1062	<0.0001
β_rl₁,age×C	1.1249	0.7986	0.1943	*−2.7472*	2.2936	0.3429
β_{rl₁,age×EGlob}	−1.7255	3.3478	0.6063	−0.3192	2.5953	0.9021
β_rl₁,age×k	0.2455	0.2185	0.2873	0.2682	0.2270	0.3430
β_rl₁,age×Q	1.5858	1.5753	0.3141	0.6680	1.5041	0.6570
β_rl₁,age×l	0.0638	0.1154	0.5803	*−0.0844*	0.1449	0.5604
β_{rl₁,age×sex}	0.1914	0.1145	0.1301	0.1999	0.1179	0.1802

β_sl₁,0	0.2290	0.0091	<0.0001	0.2253	0.0108	<0.0001
β_sl₁,C	2.2940	0.2428	<0.0001	2.2476	0.1614	<0.0001
β_sl₁,EGlob	0.9534	0.1823	<0.0001	1.0693	0.1869	<0.0001
β_sl₁,k	−0.2524	0.0153	<0.0001	−0.2438	0.0126	<0.0001
β_sl₁,Q	−0.0373	0.1723	0.8285	0.0364	0.1593	0.8195
β_sl₁,l	−0.0036	0.0109	0.7426	−0.0014	0.0115	0.9021
β_sl₁,age	−0.0106	0.0124	0.4262	−0.0080	0.0126	0.5228
β_sl₁,sex	−0.0046	0.0132	0.7263	0.0002	0.0151	0.9872
β_sl₁,educ	−0.0009	0.0017	0.5814	−0.0026	0.0015	*0.0933*
β_sl₁,dist	−0.1718	*0.0054*	<0.0001	−0.1717	0.0052	<0.0001
β_sl₁,dist²	0.3910	0.0118	<0.0001	0.3865	0.0117	<0.0001
β_sl₁,age×C	0.7214	0.3494	0.0467	0.5293	0.2508	0.0493
β_{sl₁,age×EGlob}	0.7042	0.2623	0.0097	0.6452	0.2269	0.0084
β_sl₁,age×k	0.0009	0.0220	0.9662	−0.0054	0.0208	0.7957
β_sl₁,age×Q	−0.6957	0.2464	0.0071	−0.6588	0.1996	0.0021
β_sl₁,age×l	0.0556	0.0157	0.0007	0.0464	0.0139	0.0019
β_{sl₁,age×sex}	0.0001	0.0184	0.9952	*−0.0083*	0.0181	0.6474

Parameter l₁ = rest	Rest (univariate)			Rest (with visual)^a
Parameter l₁ = rest	Estimate	SE	p value*	Estimate	SE	p value*
β_rl₁,0	−0.3141	0.0569	<0.0001	−0.2488	0.0448	<0.0001
β_rl₁,C	0.7807	0.3424	0.0355	*7.1274*	1.8466	*0.0004*
β_rl₁,EGlob	32.6231	2.3322	<0.0001	30.6695	1.3489	<0.0001
β_rl₁,k	−1.4442	0.1522	<0.0001	−1.5229	0.1782	<0.0001
β_rl₁,Q	−0.7345	1.1361	0.5179	−0.6460	0.9376	*0.4923*
β_rl₁,l	1.1598	0.0785	<0.0001	1.3824	0.0907	<0.0001
β_rl₁,age	−0.0438	0.0773	0.5709	−0.0806	0.0792	0.4229
β_rl₁,sex	−0.0085	0.0825	0.9178	−0.0452	0.0658	*0.4923*
β_rl₁,educ	0.0027	0.0103	0.7954	0.0071	0.0097	0.4923
β_rl₁,dist	−1.4266	0.0572	<0.0001	−1.4648	0.0530	<0.0001
β_rl₁,dist²	2.6558	0.1417	<0.0001	2.6309	0.1062	<0.0001
β_rl₁,age×C	1.1249	0.7986	0.1943	*−2.7472*	2.2936	0.3429
β_{rl₁,age×EGlob}	−1.7255	3.3478	0.6063	−0.3192	2.5953	0.9021
β_rl₁,age×k	0.2455	0.2185	0.2873	0.2682	0.2270	0.3430
β_rl₁,age×Q	1.5858	1.5753	0.3141	0.6680	1.5041	0.6570
β_rl₁,age×l	0.0638	0.1154	0.5803	*−0.0844*	0.1449	0.5604
β_{rl₁,age×sex}	0.1914	0.1145	0.1301	0.1999	0.1179	0.1802

β_sl₁,0	0.2290	0.0091	<0.0001	0.2253	0.0108	<0.0001
β_sl₁,C	2.2940	0.2428	<0.0001	2.2476	0.1614	<0.0001
β_sl₁,EGlob	0.9534	0.1823	<0.0001	1.0693	0.1869	<0.0001
β_sl₁,k	−0.2524	0.0153	<0.0001	−0.2438	0.0126	<0.0001
β_sl₁,Q	−0.0373	0.1723	0.8285	0.0364	0.1593	0.8195
β_sl₁,l	−0.0036	0.0109	0.7426	−0.0014	0.0115	0.9021
β_sl₁,age	−0.0106	0.0124	0.4262	−0.0080	0.0126	0.5228
β_sl₁,sex	−0.0046	0.0132	0.7263	0.0002	0.0151	0.9872
β_sl₁,educ	−0.0009	0.0017	0.5814	−0.0026	0.0015	*0.0933*
β_sl₁,dist	−0.1718	*0.0054*	<0.0001	−0.1717	0.0052	<0.0001
β_sl₁,dist²	0.3910	0.0118	<0.0001	0.3865	0.0117	<0.0001
β_sl₁,age×C	0.7214	0.3494	0.0467	0.5293	0.2508	0.0493
β_{sl₁,age×EGlob}	0.7042	0.2623	0.0097	0.6452	0.2269	0.0084
β_sl₁,age×k	0.0009	0.0220	0.9662	−0.0054	0.0208	0.7957
β_sl₁,age×Q	−0.6957	0.2464	0.0071	−0.6588	0.1996	0.0021
β_sl₁,age×l	0.0556	0.0157	0.0007	0.0464	0.0139	0.0019
β_{sl₁,age×sex}	0.0001	0.0184	0.9952	*−0.0083*	0.0181	0.6474

Adjusted using the adaptive FDR procedure detailed in Benjamini and Hochberg (2000).

Bold and italicized values indicate substantial differences in the estimated relationships between covariates and network connectivity at rest resulting from the leveraging of visual task information in the model.

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