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Table 1. 

Sample Characteristics

HCPD
AllLevoMonoDual TherapyDAAMono
Sample size (n56 55 25 20 10 
Age (years) 62.2 (7.0) 63.7 (8.1) 65.5 (9.1) 61.5 (6.7) 63.7 (7.8) 
Sex (M:F) 29:27 236:19 19:6 13:7 4:6 
Education (years) 16.2 (3.2) 15.5 (2.5) 15.8 (2.3) 15.2 (2.6) 15.2 (2.7) 
MOCA* (n = 26) 28.1 (1.4) 26.0 (2.4) 25.8 (2.5) 26.5 (2.4) 25.1 (2.4) 
MMSE (n = 30) 29.5 (1.0)     
QUIP-ICD – 10.3 (7.4) 9.3 (6.9) 11.2 (6.9) 11.1 (9.7) 
QUIP-Total – 21.5 (13.5) 20.6 (13.0) 21.8 (11.5) 23.3 (19.0) 
LEDD** – 732.0 (431.2) 707.2 (405.4) 1006.0 (332.1) 246.0 (116.3) 
Disease duration (years)*** – 4.4 (3.4) 3.2 (2.4) 6.3 (3.7) 3.3 (3.5) 
UPDRS motor – 26.9 (12.8) 23.8 (10.6) 32.1 (14.1) 23.8 (12.6) 
HCPD
AllLevoMonoDual TherapyDAAMono
Sample size (n56 55 25 20 10 
Age (years) 62.2 (7.0) 63.7 (8.1) 65.5 (9.1) 61.5 (6.7) 63.7 (7.8) 
Sex (M:F) 29:27 236:19 19:6 13:7 4:6 
Education (years) 16.2 (3.2) 15.5 (2.5) 15.8 (2.3) 15.2 (2.6) 15.2 (2.7) 
MOCA* (n = 26) 28.1 (1.4) 26.0 (2.4) 25.8 (2.5) 26.5 (2.4) 25.1 (2.4) 
MMSE (n = 30) 29.5 (1.0)     
QUIP-ICD – 10.3 (7.4) 9.3 (6.9) 11.2 (6.9) 11.1 (9.7) 
QUIP-Total – 21.5 (13.5) 20.6 (13.0) 21.8 (11.5) 23.3 (19.0) 
LEDD** – 732.0 (431.2) 707.2 (405.4) 1006.0 (332.1) 246.0 (116.3) 
Disease duration (years)*** – 4.4 (3.4) 3.2 (2.4) 6.3 (3.7) 3.3 (3.5) 
UPDRS motor – 26.9 (12.8) 23.8 (10.6) 32.1 (14.1) 23.8 (12.6) 

Values provided are means (with standard deviation in parentheses).

AMNART = American modification of the National Adult Reading Test; CES-D = Center for Epidemiological Studies-Depression Scale; DAA = dopamine agonist monotherapy; Levo Mono = levodopa monotherapy; MMSE = Mini Mental Status Examination; QUIP = Questionnaire for Impulsive-Compulsive Disorders (ICD includes only the following behaviors: gambling, sexual behavior, buying, and eating).

*

p < .05, comparing HC with MOCA (n = 26) to all PD.

**

p < .05, contrasting DAA Mono to Levo Mono and Dual Therapy.

***

p < .05, contrasting Dual Therapy to DAA Mono and Levo Mono.

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