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Table 6. 

Regions Showing Increased Functional Connectivity with Specific Seed Areas as a Function of Experimental Condition (O > V and V > O) and Group (Blind > Sighted)

Areakx (mm)y (mm)z (mm)Zp
PPI [EB > SC] × [V > O] 
Seed areas in voice-selective regions common to EB and SC 
 L superior temporal sulcus [−60 −28 0] 
  R anterior fusiform G 42 −46 −8 3.24 .041 
 R superior temporal sulcus [62 −24 0] 
  No significant voxels 
 
PPI [EB > SC] × [O > V] 
Seed areas in object-selective regions common to EB and SC 
 L transverse temporal sulcus (A1) [−42 −22 −2] 
  L inferior occipital G −44 −74 −14 3.11 .056# 
 L transverse temporal G [−42 −34 18] 
  L fusiform 12 −34 −62 −16 3.88 .006 
  L inferior occipital G −44 −76 −14 3.34 .032 
 R planum temporale [46 −30 16] 
  R anterior fusiform G 46 −38 −20 3.18 .052# 
 L inferior frontal G [−32 30 −8] 
  L posterior fusiform G 101 −38 −66 −14 3.79 .007 
 L inferior frontal S [−46 40 12] 
  L posterior fusiform G 160 −34 −68 −12 3.71 .011 
  R anterior fusiform G 36 −34 −24 3.16 .05# 
 L pMTG [−54 −60 2] 
  R anterior fusiform G 40 −36 −22 3.8 .008 
  L posterior fusiform G 19 −38 −66 −14 3.57 .017 
 L inferior temporal S [−44 −50 −12] 
  L posterior fusiform G 37 −38 −64 −14 3.87 .006 
  L inferior occipital G −38 −80 −10 3.22 .044 
 
PPI [EB > SC] × [O > V] 
Seed areas in object-selective regions specific to EB 
 L middle occipital G [−26 −92 6] 
  L posterior fusiform G 178 −36 −64 −12 4.07 .003 
  R anterior fusiform G 14 44 −38 −20 3.48 .021 
  R planum temporale 30 50 −36 3.80 .008 
  R middle occipital G 19 50 −74 3.46 .022 
 L inferior/middle occipital G [−36 −82 −2] 
  R inferior occipital G 14 50 −74 3.94 .005 
  L inferior temporal/fusiform G 112 −46 −68 −6 3.82 .008 
 R middle occipital G [40 −86 10] 
  L posterior fusiform G 202 −34 −64 −16 4.12 .002 
  R planum temporale 84 52 −34 4.11 .002 
 R middle/inferior occipital G [36 −80 −2] 
  L posterior fusiform G 13 −36 −66 −16 3.27 .038 
Areakx (mm)y (mm)z (mm)Zp
PPI [EB > SC] × [V > O] 
Seed areas in voice-selective regions common to EB and SC 
 L superior temporal sulcus [−60 −28 0] 
  R anterior fusiform G 42 −46 −8 3.24 .041 
 R superior temporal sulcus [62 −24 0] 
  No significant voxels 
 
PPI [EB > SC] × [O > V] 
Seed areas in object-selective regions common to EB and SC 
 L transverse temporal sulcus (A1) [−42 −22 −2] 
  L inferior occipital G −44 −74 −14 3.11 .056# 
 L transverse temporal G [−42 −34 18] 
  L fusiform 12 −34 −62 −16 3.88 .006 
  L inferior occipital G −44 −76 −14 3.34 .032 
 R planum temporale [46 −30 16] 
  R anterior fusiform G 46 −38 −20 3.18 .052# 
 L inferior frontal G [−32 30 −8] 
  L posterior fusiform G 101 −38 −66 −14 3.79 .007 
 L inferior frontal S [−46 40 12] 
  L posterior fusiform G 160 −34 −68 −12 3.71 .011 
  R anterior fusiform G 36 −34 −24 3.16 .05# 
 L pMTG [−54 −60 2] 
  R anterior fusiform G 40 −36 −22 3.8 .008 
  L posterior fusiform G 19 −38 −66 −14 3.57 .017 
 L inferior temporal S [−44 −50 −12] 
  L posterior fusiform G 37 −38 −64 −14 3.87 .006 
  L inferior occipital G −38 −80 −10 3.22 .044 
 
PPI [EB > SC] × [O > V] 
Seed areas in object-selective regions specific to EB 
 L middle occipital G [−26 −92 6] 
  L posterior fusiform G 178 −36 −64 −12 4.07 .003 
  R anterior fusiform G 14 44 −38 −20 3.48 .021 
  R planum temporale 30 50 −36 3.80 .008 
  R middle occipital G 19 50 −74 3.46 .022 
 L inferior/middle occipital G [−36 −82 −2] 
  R inferior occipital G 14 50 −74 3.94 .005 
  L inferior temporal/fusiform G 112 −46 −68 −6 3.82 .008 
 R middle occipital G [40 −86 10] 
  L posterior fusiform G 202 −34 −64 −16 4.12 .002 
  R planum temporale 84 52 −34 4.11 .002 
 R middle/inferior occipital G [36 −80 −2] 
  L posterior fusiform G 13 −36 −66 −16 3.27 .038 

Seed areas are the ones resulting from the activation analyses (depicted in Figures 2A and B, 3A, and 4A). Regions showing increased connectivity with these seed areas in the blind group compared with the sighted group are listed in this table and are depicted in Figures 2D and 4B. Coordinates reported in this table are significant (p < .05 FWE) after correction over small spherical volumes (SVC). Marginally significant clusters are indicated with (#). EB = early blind; SC = sighted controls; V = voices; O = objects; L = left; R = right; G = gyrus; S = sulcus. Coordinates used for correction over small spherical volumes are as follows (in MNI space): R fusiform G: [40 −36 −10] (Hölig et al., 2014); L fusiform G: [−36 −63 −18] (Noppeney et al., 2003); L inferior occipital G: [−36 −81 −15] (Noppeney et al., 2003); R planum temporale: [52 −44 10] (Lewis, Talkington, et al., 2011); R middle occipital G: [44 −74 8] (Gougoux et al., 2009).

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