Table 4. 
Imaging: Data items extracted for characterization and appraisal
Data item
What is the imaging modality? If PET, what metabolic parameter is estimated? 
Is the study cross-sectional or longitudinal? If the study is longitudinal, is it a study of spontaneous recovery, a treatment study in the chronic period, or a treatment study in the period during which spontaneous recovery would also be expected? 
If the study is longitudinal, at what time point(s) were imaging data acquired? 
If the study is longitudinal, was there any intervention between the time points at which imaging data were acquired? 
Is the make and model of the scanner described? 
Is the design blocked or event-related? 
Is the timing of stimulus presentation (e.g., block length, trials per block) and image acquisition (e.g., number of volumes, repetition time) clearly described and appropriate? 
Are the imaging acquisition parameters, including coverage, adequately described and appropriate? 
Is preprocessing and intrasubject coregistration adequately described and appropriate? 
10 Is first level model fitting adequately described and appropriate? 
11 Is intersubject normalization adequately described and appropriate? 
Data item
What is the imaging modality? If PET, what metabolic parameter is estimated? 
Is the study cross-sectional or longitudinal? If the study is longitudinal, is it a study of spontaneous recovery, a treatment study in the chronic period, or a treatment study in the period during which spontaneous recovery would also be expected? 
If the study is longitudinal, at what time point(s) were imaging data acquired? 
If the study is longitudinal, was there any intervention between the time points at which imaging data were acquired? 
Is the make and model of the scanner described? 
Is the design blocked or event-related? 
Is the timing of stimulus presentation (e.g., block length, trials per block) and image acquisition (e.g., number of volumes, repetition time) clearly described and appropriate? 
Are the imaging acquisition parameters, including coverage, adequately described and appropriate? 
Is preprocessing and intrasubject coregistration adequately described and appropriate? 
10 Is first level model fitting adequately described and appropriate? 
11 Is intersubject normalization adequately described and appropriate? 

Note. PET = positron emission tomography.

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