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Table 3. 

Differential Activation Sites According to Semantic Distance

Anatomical Regions
Coordinates (x, y, z)
Z
Cluster Size
p
Low SemD > High SemD 
Frontal cortex 
 L Middle frontal gyrus, BA 6 −22, −4, 54 4.03 227 .008 
 L Inferior frontal gyrus, BA 44 −50, 16, 22 4.69 970 <.001 
 L Inferior frontal gyrus, BA 45 −50, 32, 24 3.95 
 L Insula −34, 22, 0 5.17 442 <.001 
 R Middle frontal gyrus, BA 6 30, 4, 58 4.54 365 <.001 
 R Middle frontal gyrus, BA 46 50, 38, 24 4.51 453 <.001 
 R Inferior frontal gyrus, BA 44 46, 10, 28 4.10 
 R Insula 30, 26, −2 5.82 520 <.001 
Other 
 L Superior parietal lobule, BA 7 −20, −64, 48 4.86 800 <.001 
 R Anterior cingulate, BA 32 4, 16, 48 5.68 1260 <.001 
 Anterior cingulate, BA 32 0, 32, 44 4.44 
 
High SemD > Low SemD 
Frontal cortex 
 L Superior frontal gyrus, BA 9 −22, 24, 38 5.15 519 <.001 
 L Middle frontal gyrus, BA 9 −20, 42, 36 3.24 
 R Superior frontal gyrus, BA 10 10, 66, 10 6.03 2722 <.001 
 L Superior frontal gyrus, BA 10 −10, 46, −6 5.01 
Anterior temporal cortex 
 L Middle temporal gyrus, BA 21 −62, −16, −16 5.28 316 .001 
 R Middle temporal gyrus, BA 21 62, −8, −22 4.37 247 .005 
Other 
 L Middle cingulate, BA 23 −2, −18, 40 5.05 2771 <.001 
 L Posterior cingulate, BA 30 −12, −62, 14 4.88 
 L Posterior cingulate, BA 23 −4, −60, 30 4.81 
 L Angular gyrus, BA 39 −48, −72, 36 4.05 191 .018 
Anatomical Regions
Coordinates (x, y, z)
Z
Cluster Size
p
Low SemD > High SemD 
Frontal cortex 
 L Middle frontal gyrus, BA 6 −22, −4, 54 4.03 227 .008 
 L Inferior frontal gyrus, BA 44 −50, 16, 22 4.69 970 <.001 
 L Inferior frontal gyrus, BA 45 −50, 32, 24 3.95 
 L Insula −34, 22, 0 5.17 442 <.001 
 R Middle frontal gyrus, BA 6 30, 4, 58 4.54 365 <.001 
 R Middle frontal gyrus, BA 46 50, 38, 24 4.51 453 <.001 
 R Inferior frontal gyrus, BA 44 46, 10, 28 4.10 
 R Insula 30, 26, −2 5.82 520 <.001 
Other 
 L Superior parietal lobule, BA 7 −20, −64, 48 4.86 800 <.001 
 R Anterior cingulate, BA 32 4, 16, 48 5.68 1260 <.001 
 Anterior cingulate, BA 32 0, 32, 44 4.44 
 
High SemD > Low SemD 
Frontal cortex 
 L Superior frontal gyrus, BA 9 −22, 24, 38 5.15 519 <.001 
 L Middle frontal gyrus, BA 9 −20, 42, 36 3.24 
 R Superior frontal gyrus, BA 10 10, 66, 10 6.03 2722 <.001 
 L Superior frontal gyrus, BA 10 −10, 46, −6 5.01 
Anterior temporal cortex 
 L Middle temporal gyrus, BA 21 −62, −16, −16 5.28 316 .001 
 R Middle temporal gyrus, BA 21 62, −8, −22 4.37 247 .005 
Other 
 L Middle cingulate, BA 23 −2, −18, 40 5.05 2771 <.001 
 L Posterior cingulate, BA 30 −12, −62, 14 4.88 
 L Posterior cingulate, BA 23 −4, −60, 30 4.81 
 L Angular gyrus, BA 39 −48, −72, 36 4.05 191 .018 

Anatomical and Brodmann's areas, MNI coordinates of the maxima within each cluster, Z values, cluster size, and p values corrected at cluster level of the regions that showed a main effect of the considered variables. Coordinates are in millimeters: x = distance to right (+) or left (−) of the mid-sagittal plane; y = distance anterior (+) or posterior (−) to vertical plane through anterior commissure; z = distance above (+) or below (−) intercommissural (AC–PC) line.

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