Demographic and Baseline Clinical Characteristics of Participants (Engel Classes 1 and 2 Only, N = 32, Mean ± SD)
| . | All Participants . | Left ATLR . | Right ATLR . | p . |
|---|---|---|---|---|
| Demographic and Clinical Characteristics | ||||
| Number of participants | N = 32 | N = 14 | N = 18 | |
| Age at surgery (years, range) | 35.53 (16–63) | 36.57 ± 9.35 | 34.72 ± 13.54 | .666 |
| Sex (male/female) | 17/15 | 8/6 | 9/9 | .688 |
| Education (years) | 15.0 ± 2.77 | 15.00 ± 2.08 | 15.00 ± 3.12 | 1.00 |
| Ethnicity | ||||
| White | 23 (71.9%) | 10 | 13 | .735 (Fisher's exact) |
| Black | 4 (12.5%) | 2 | 2 | |
| Hispanic | 4 (12.5%) | 2 | 2 | |
| Asian | 1 (3.1%) | 0 | 1 | |
| Handedness (right/left/ambidextrous) | 23/8/1 | 10/4/0 | 13/4/1 | .636 |
| Age at seizure onset (years) | 15.06 (1–47) | 15.71 ± 10.36 | 14.56 ± 11.24 | .767 |
| Duration of seizures (years) | 18.88 ± 14.18 | 18.93 ± 13.34 | 18.83 ± 15.18 | .985 |
| Years of follow-up after surgery (years) | 2.41 ± 1.45 | 2.51 ± 1.46 | 2.34 ± 1.50 | .763 |
| Mesial temporal sclerosis | 13/17 (40.6%/53.1%) | 4/9 | 9/8 | .283 |
| Engel class outcome | ||||
| Class 1 | 27 (84.4%) | 11 | 16 | .631 |
| Class 2 | 5 (15.6%) | 3 | 2 | |
| Baseline Neuropsychological Testing | ||||
| FSIQ | 99.04 ± 13.76 | 98.83 ± 13.99 | 99.19 ± 14.05 | .948 |
| Verbal Comprehension Index | 100.5 ± 19.82 | 94.36 ± 18.98 | 105.28 ± 19.64 | .124 |
| Perceptual Reasoning Index | 98.84 ± 15.39 | 101.14 ± 17.77 | 97.06 ± 13.51 | .465 |
| Working Memory Index | 93.78 ± 18.64 | 99.50 ± 10.06 | 89.50 ± 22.49 | .164 |
| Processing Speed Index | 93.72 ± 19.71 | 97.75 ± 10.91 | 90.88 ± 24.02 | .365 |
| Verbal Learning | 46.81 ± 12.89 | 45.14 ± 14.69 | 46.33 ± 9.94 | .404 |
| Verbal SDFR | 8.85 ± 3.53 | 8.21 ± 3.42 | 8.58 ± 3.58 | .190 |
| Verbal LDFR | 9.42 ± 3.67 | 8.71 ± 3.47 | 9.58 ± 3.42 | .346 |
| Visual Confrontation Naming (BNT) | 50.20 ± 7.30 | 48.93 ± 6.96 | 51.31 ± 7.64 | .382 |
| Visual Memory (RCFT delay trial) | 12.90 ± 6.48 | 14.00 ± 7.47 | 12.17 ± 5.84 | .458 |
| BDI | 9.26 ± 5.73 | 9.15 ± 5.90 | 9.36 ± 5.79 | .929 |
| BAI | 11.32 ± 11.35 | 12.07 ± 12.69 | 10.57 ± 10.26 | .734 |
| Left Wada memory score | 9.03 ± 3.52 | 7.64 ± 3.97 | 10.18± 2.72 | .055 |
| Right Wada memory score | 7.32 ± 3.32 | 8.29 ± 2.64 | 6.47 ± 3.70 | .138 |
| Wada language (left/right/bilateral) | 30/0/1 | 13/0/1 | 17/0/0 | .452 (Fisher's exact) |
| Postsurgical Neuropsychological Testing | ||||
| FSIQ | 99.61 ± 14.61 | 99.25 ± 11.35 | 99.88 ± 17.02 | .913 |
| Verbal Comprehension Index | 103.93 ± 15.02 | 101.00 ± 9.83 | 106.00 ± 17.82 | .387 |
| Perceptual Reasoning Index | 99.45 ± 13.58 | 101.33 ± 11.74 | 98.12 ± 14.95 | .540 |
| Working Memory Index | 100.56 ± 14.76 | 103.45 ± 13.78 | 98.56 ± 15.50 | .408 |
| Processing Speed Index | 97.18 ± 14.01 | 96.42 ± 14.79 | 97.75 ± 13.87 | .809 |
| Verbal Learning | 42.56 ± 10.81 | 39.08 ± 10.77 | 46.33 ± 9.94 | .094 |
| Verbal SDFR | 6.92 ± 3.67 | 5.38 ± 3.15 | 8.58 ± 3.58 | .026 |
| Verbal LDFR | 7.60 ±4.26 | 5.77 ± 4.30 | 9.58 ± 3.34 | .022 |
| Visual Confrontation Naming (BNT) | 48.30 ± 8.81 | 44.36 ± 9.52 | 52.54 ± 5.70 | .012 |
| Visual Memory (RCFT delay trial) | 10.97 ± 5.17 | 12.69 ± 5.66 | 9.56 ± 4.43 | .106 |
| BDI | 8.13 ± 7.32 | 9.36 ± 8.23 | 7.12 ± 6.56 | .406 |
| BAI | 6.84 ± 6.40 | 8.29 ± 7.97 | 5.64 ± 4.67 | .260 |
| . | All Participants . | Left ATLR . | Right ATLR . | p . |
|---|---|---|---|---|
| Demographic and Clinical Characteristics | ||||
| Number of participants | N = 32 | N = 14 | N = 18 | |
| Age at surgery (years, range) | 35.53 (16–63) | 36.57 ± 9.35 | 34.72 ± 13.54 | .666 |
| Sex (male/female) | 17/15 | 8/6 | 9/9 | .688 |
| Education (years) | 15.0 ± 2.77 | 15.00 ± 2.08 | 15.00 ± 3.12 | 1.00 |
| Ethnicity | ||||
| White | 23 (71.9%) | 10 | 13 | .735 (Fisher's exact) |
| Black | 4 (12.5%) | 2 | 2 | |
| Hispanic | 4 (12.5%) | 2 | 2 | |
| Asian | 1 (3.1%) | 0 | 1 | |
| Handedness (right/left/ambidextrous) | 23/8/1 | 10/4/0 | 13/4/1 | .636 |
| Age at seizure onset (years) | 15.06 (1–47) | 15.71 ± 10.36 | 14.56 ± 11.24 | .767 |
| Duration of seizures (years) | 18.88 ± 14.18 | 18.93 ± 13.34 | 18.83 ± 15.18 | .985 |
| Years of follow-up after surgery (years) | 2.41 ± 1.45 | 2.51 ± 1.46 | 2.34 ± 1.50 | .763 |
| Mesial temporal sclerosis | 13/17 (40.6%/53.1%) | 4/9 | 9/8 | .283 |
| Engel class outcome | ||||
| Class 1 | 27 (84.4%) | 11 | 16 | .631 |
| Class 2 | 5 (15.6%) | 3 | 2 | |
| Baseline Neuropsychological Testing | ||||
| FSIQ | 99.04 ± 13.76 | 98.83 ± 13.99 | 99.19 ± 14.05 | .948 |
| Verbal Comprehension Index | 100.5 ± 19.82 | 94.36 ± 18.98 | 105.28 ± 19.64 | .124 |
| Perceptual Reasoning Index | 98.84 ± 15.39 | 101.14 ± 17.77 | 97.06 ± 13.51 | .465 |
| Working Memory Index | 93.78 ± 18.64 | 99.50 ± 10.06 | 89.50 ± 22.49 | .164 |
| Processing Speed Index | 93.72 ± 19.71 | 97.75 ± 10.91 | 90.88 ± 24.02 | .365 |
| Verbal Learning | 46.81 ± 12.89 | 45.14 ± 14.69 | 46.33 ± 9.94 | .404 |
| Verbal SDFR | 8.85 ± 3.53 | 8.21 ± 3.42 | 8.58 ± 3.58 | .190 |
| Verbal LDFR | 9.42 ± 3.67 | 8.71 ± 3.47 | 9.58 ± 3.42 | .346 |
| Visual Confrontation Naming (BNT) | 50.20 ± 7.30 | 48.93 ± 6.96 | 51.31 ± 7.64 | .382 |
| Visual Memory (RCFT delay trial) | 12.90 ± 6.48 | 14.00 ± 7.47 | 12.17 ± 5.84 | .458 |
| BDI | 9.26 ± 5.73 | 9.15 ± 5.90 | 9.36 ± 5.79 | .929 |
| BAI | 11.32 ± 11.35 | 12.07 ± 12.69 | 10.57 ± 10.26 | .734 |
| Left Wada memory score | 9.03 ± 3.52 | 7.64 ± 3.97 | 10.18± 2.72 | .055 |
| Right Wada memory score | 7.32 ± 3.32 | 8.29 ± 2.64 | 6.47 ± 3.70 | .138 |
| Wada language (left/right/bilateral) | 30/0/1 | 13/0/1 | 17/0/0 | .452 (Fisher's exact) |
| Postsurgical Neuropsychological Testing | ||||
| FSIQ | 99.61 ± 14.61 | 99.25 ± 11.35 | 99.88 ± 17.02 | .913 |
| Verbal Comprehension Index | 103.93 ± 15.02 | 101.00 ± 9.83 | 106.00 ± 17.82 | .387 |
| Perceptual Reasoning Index | 99.45 ± 13.58 | 101.33 ± 11.74 | 98.12 ± 14.95 | .540 |
| Working Memory Index | 100.56 ± 14.76 | 103.45 ± 13.78 | 98.56 ± 15.50 | .408 |
| Processing Speed Index | 97.18 ± 14.01 | 96.42 ± 14.79 | 97.75 ± 13.87 | .809 |
| Verbal Learning | 42.56 ± 10.81 | 39.08 ± 10.77 | 46.33 ± 9.94 | .094 |
| Verbal SDFR | 6.92 ± 3.67 | 5.38 ± 3.15 | 8.58 ± 3.58 | .026 |
| Verbal LDFR | 7.60 ±4.26 | 5.77 ± 4.30 | 9.58 ± 3.34 | .022 |
| Visual Confrontation Naming (BNT) | 48.30 ± 8.81 | 44.36 ± 9.52 | 52.54 ± 5.70 | .012 |
| Visual Memory (RCFT delay trial) | 10.97 ± 5.17 | 12.69 ± 5.66 | 9.56 ± 4.43 | .106 |
| BDI | 8.13 ± 7.32 | 9.36 ± 8.23 | 7.12 ± 6.56 | .406 |
| BAI | 6.84 ± 6.40 | 8.29 ± 7.97 | 5.64 ± 4.67 | .260 |
Independent samples t test comparison performed with p values listed.
Significant after correction for multiple comparisons.