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Table 1.

Search criteria, number of papers found in the Web of Science (WoS), number of papers selected and number of papers forming the cofunding network models. It is important to note that because of the historical relevance of Cas9 and Cas12a as the first two CRISPR platforms for genome editing (Ishino, Krupovic, & Forterre, 2018) we use them as additional terms in the search criteria, and the search for terms in WoS was carried out as a full-text search, not limited to terms in the title. Thus, although we did not explicitly search for the different nucleases (and their pseudonyms), any paper with a term associated with CRISPR will appear in the search. This scope is important because the two university systems have distinct IP rights over the Cas variants and we aimed to be as inclusive as possible.

Broad/Harvard/MIT System 
Search criteria: 
ORGANIZATION-ENHANCED: (Broad Institute or Massachusetts Institute of Technology (MIT) or Harvard University) AND TOPIC: (CRISPR or “clustered regularly interspaced short palindromic repeats” or Cas9 or Cpf1 or Cas12a). Refined by: DOCUMENT TYPES: (ARTICLE) 
Total of papers found in the WoS (by April 25, 2020) 922 
Total of papers selected from WoS with at least 25 citations (receiving 95.2% of citations) 364 
University of California System 
Search criteria: 
ORGANIZATION-ENHANCED: (University of California System) AND TOPIC: (CRISPR or “clustered regularly interspaced short palindromic repeats” or Cas9 or Cpf1 or Cas12a). Refined by: DOCUMENT TYPES: (ARTICLE) 
Total of papers found in the WoS (by April 25, 2020) 920 
Total of papers selected from WoS with at least 15 citations (receiving 94.8% of citations) 400 
Broad/Harvard/MIT System 
Search criteria: 
ORGANIZATION-ENHANCED: (Broad Institute or Massachusetts Institute of Technology (MIT) or Harvard University) AND TOPIC: (CRISPR or “clustered regularly interspaced short palindromic repeats” or Cas9 or Cpf1 or Cas12a). Refined by: DOCUMENT TYPES: (ARTICLE) 
Total of papers found in the WoS (by April 25, 2020) 922 
Total of papers selected from WoS with at least 25 citations (receiving 95.2% of citations) 364 
University of California System 
Search criteria: 
ORGANIZATION-ENHANCED: (University of California System) AND TOPIC: (CRISPR or “clustered regularly interspaced short palindromic repeats” or Cas9 or Cpf1 or Cas12a). Refined by: DOCUMENT TYPES: (ARTICLE) 
Total of papers found in the WoS (by April 25, 2020) 920 
Total of papers selected from WoS with at least 15 citations (receiving 94.8% of citations) 400 
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