Pauling’s view of his own model (no competing model)
Probability . | Estimate . | Description . | Evidence . |
---|---|---|---|
P(T) | 0.5 | neutral | prior of T |
P(∼T) | 0.5 | neutral | 1 − prior |
P(E1|T) | 0.6 | weakly consistent | analogy to alpha helix |
P(E1|∼T) | 0.5 | neutral | hypothetical null model |
P(E2|T) | 0.6 | weakly consistent | X-ray data (Astbury) |
P(E2|∼T) | 0.5 | neutral | hypothetical null model |
P(E3|T) | 0.3 | strongly inconsistent | bond lengths/angles wrong |
P(E3|∼T) | 0.5 | neutral | hypothetical null model |
P(T|E1–E3) | 0.46 | disconfirm | % change = −8.0, LR = 0.86 |
Probability . | Estimate . | Description . | Evidence . |
---|---|---|---|
P(T) | 0.5 | neutral | prior of T |
P(∼T) | 0.5 | neutral | 1 − prior |
P(E1|T) | 0.6 | weakly consistent | analogy to alpha helix |
P(E1|∼T) | 0.5 | neutral | hypothetical null model |
P(E2|T) | 0.6 | weakly consistent | X-ray data (Astbury) |
P(E2|∼T) | 0.5 | neutral | hypothetical null model |
P(E3|T) | 0.3 | strongly inconsistent | bond lengths/angles wrong |
P(E3|∼T) | 0.5 | neutral | hypothetical null model |
P(T|E1–E3) | 0.46 | disconfirm | % change = −8.0, LR = 0.86 |