Table 4. 

Watson and Crick’s (W/C) view of Pauling’s model (competing model is the W/C triple helix)

ProbabilityEstimateDescriptionEvidence
P(T) 0.24 prior posterior of W/C triple helix 
P(∼T) 0.76 prior of ∼T 1 − P(T) 
P(E1|T) 0.6 weakly consistent analogy to alpha helix 
P(E1|∼T) 0.6 weakly consistent same as W/C triple helix 
P(E2|T) 0.6 weakly consistent X-ray data (Astbury) 
P(E2|∼T) 0.6 weakly consistent X-ray data (Franklin A-form) 
P(E3|T) 0.3 strongly inconsistent lack of acidity of DNA 
P(E3|∼T) 0.5 neutral not known for W/C triple helix 
P(E4|T) 0.3 strongly inconsistent bond lengths/angles wrong 
P(E4|∼T) 0.3 strongly inconsistent same as W/C triple helix 
P(T|E1–E4) 0.16 disconfirm % change= −33.3, LR = 0.6 
ProbabilityEstimateDescriptionEvidence
P(T) 0.24 prior posterior of W/C triple helix 
P(∼T) 0.76 prior of ∼T 1 − P(T) 
P(E1|T) 0.6 weakly consistent analogy to alpha helix 
P(E1|∼T) 0.6 weakly consistent same as W/C triple helix 
P(E2|T) 0.6 weakly consistent X-ray data (Astbury) 
P(E2|∼T) 0.6 weakly consistent X-ray data (Franklin A-form) 
P(E3|T) 0.3 strongly inconsistent lack of acidity of DNA 
P(E3|∼T) 0.5 neutral not known for W/C triple helix 
P(E4|T) 0.3 strongly inconsistent bond lengths/angles wrong 
P(E4|∼T) 0.3 strongly inconsistent same as W/C triple helix 
P(T|E1–E4) 0.16 disconfirm % change= −33.3, LR = 0.6 
View Large
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. No content on this site may be used to train artificial intelligence systems without permission in writing from the MIT Press.
Accept