Probability
. | Estimate
. | Description
. | Evidence
. |
---|---|---|---|

P(T) | 0.24 | prior | posterior of W/C triple helix |

P(∼T) | 0.76 | prior of ∼T | 1 − P(T) |

P(E1|T) | 0.6 | weakly consistent | analogy to alpha helix |

P(E1|∼T) | 0.6 | weakly consistent | same as W/C triple helix |

P(E2|T) | 0.6 | weakly consistent | X-ray data (Astbury) |

P(E2|∼T) | 0.6 | weakly consistent | X-ray data (Franklin A-form) |

P(E3|T) | 0.3 | strongly inconsistent | lack of acidity of DNA |

P(E3|∼T) | 0.5 | neutral | not known for W/C triple helix |

P(E4|T) | 0.3 | strongly inconsistent | bond lengths/angles wrong |

P(E4|∼T) | 0.3 | strongly inconsistent | same as W/C triple helix |

P(T|E1–E4) | 0.16 | disconfirm | % change= −33.3, LR = 0.6 |

Probability
. | Estimate
. | Description
. | Evidence
. |
---|---|---|---|

P(T) | 0.24 | prior | posterior of W/C triple helix |

P(∼T) | 0.76 | prior of ∼T | 1 − P(T) |

P(E1|T) | 0.6 | weakly consistent | analogy to alpha helix |

P(E1|∼T) | 0.6 | weakly consistent | same as W/C triple helix |

P(E2|T) | 0.6 | weakly consistent | X-ray data (Astbury) |

P(E2|∼T) | 0.6 | weakly consistent | X-ray data (Franklin A-form) |

P(E3|T) | 0.3 | strongly inconsistent | lack of acidity of DNA |

P(E3|∼T) | 0.5 | neutral | not known for W/C triple helix |

P(E4|T) | 0.3 | strongly inconsistent | bond lengths/angles wrong |

P(E4|∼T) | 0.3 | strongly inconsistent | same as W/C triple helix |

P(T|E1–E4) | 0.16 | disconfirm | % change= −33.3, LR = 0.6 |

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