Table 6.

Watson and Crick’s final double helix model (like-with-like as the alternative)

ProbabilityEstimateInterpretationEvidence
P(T0.32 prior of T posterior of like-with-like model 
P(∼T0.68 prior of not T 1 − prior 
P(E1|T0.7 strongly consistent X-ray picture of B-form supports helix via theory 
P(E1|∼T0.7 strongly consistent Like-with-like model is also a helix 
P(E2|T0.7 strongly consistent 34 Å crystallographic repeat (B form X-ray picture) 
P(E2|∼T0.3 strongly inconsistent Like-with-like model did not give a 34 Å repeat 
P(E3|T0.7 strongly consistent bond lengths fit 
P(E3|∼T0.3 strongly inconsistent Like-with-like bond lengths did not fit 
P(E4|T0.7 strongly consistent C2 symmetry of structure 
P(E4|∼T0.3 strongly inconsistent Like-with-like model lacked C2 symmetry 
P(E5|T0.7 strongly consistent obeys Chargaff’s rules 
P(E5|∼T0.3 strongly inconsistent Like-with-like inconsistent with Chargaff rules 
P(E6|T0.7 strongly consistent hydrogen bonding of bases correct 
P(E6|∼T0.3 strongly inconsistent Like-with-like model has hydrogen bonding wrong 
P(E7|T0.6 weakly consistent mechanism for replication suggested 
P(E7|∼T0.6 weakly consistent Like-with-like also gave mechanism for replication 
P(T|E1–E7) 0.97 Confirm % change = +203.1, LR = 69.2 
ProbabilityEstimateInterpretationEvidence
P(T0.32 prior of T posterior of like-with-like model 
P(∼T0.68 prior of not T 1 − prior 
P(E1|T0.7 strongly consistent X-ray picture of B-form supports helix via theory 
P(E1|∼T0.7 strongly consistent Like-with-like model is also a helix 
P(E2|T0.7 strongly consistent 34 Å crystallographic repeat (B form X-ray picture) 
P(E2|∼T0.3 strongly inconsistent Like-with-like model did not give a 34 Å repeat 
P(E3|T0.7 strongly consistent bond lengths fit 
P(E3|∼T0.3 strongly inconsistent Like-with-like bond lengths did not fit 
P(E4|T0.7 strongly consistent C2 symmetry of structure 
P(E4|∼T0.3 strongly inconsistent Like-with-like model lacked C2 symmetry 
P(E5|T0.7 strongly consistent obeys Chargaff’s rules 
P(E5|∼T0.3 strongly inconsistent Like-with-like inconsistent with Chargaff rules 
P(E6|T0.7 strongly consistent hydrogen bonding of bases correct 
P(E6|∼T0.3 strongly inconsistent Like-with-like model has hydrogen bonding wrong 
P(E7|T0.6 weakly consistent mechanism for replication suggested 
P(E7|∼T0.6 weakly consistent Like-with-like also gave mechanism for replication 
P(T|E1–E7) 0.97 Confirm % change = +203.1, LR = 69.2 
Close Modal

or Create an Account

Close Modal
Close Modal